Polycystic kidney disease (PKD) is the name for a range of life-threatening inherited disorders that can cause kidney failure and damage to other organs. Faulty genes cause fluid-filled cysts to develop and grow in the kidneys. This can happen at any point during childhood or adulthood and as they get bigger they cause the kidneys to enlarge – sometimes to three or four times their normal size.   Symptoms of PKD may include any of the following:  • Abdominal pain or tenderness   • Blood in the urine • Excessive urination at night  • Flank pain on one or both sides   • Drowsiness   • Joint pain   • Nail abnormalities Health problems that may result from PKD include:  • Anemia  • Bleeding or rupture of cysts  • Long-term (chronic) kidney disease  • End-stage kidney disease  • High blood pressure • Infection of liver cysts  • Kidney stones   • Liver failure (mild to severe)  • Repeated ...